Pseudomonas Aeruginosa Essays - Gram-negative Bacteria,

Pseudomonas Aeruginosa Pseudomonas aeruginosa Research Paper Julie Johnson Pseudomonas aeruginosa is a versatile gram negative bacterium that grows in soil, marshes, and coastal marine habitats, as well as on plant and animal tissues. People with cystic fibrosis, burn victims, individuals with cancer, and persons infected with HIV are particularly at risk of disease resulting from Pseudomonas aeruginosa. Unlike many environmental bacteria, Pseudomonas aeruginosa has a remarkable capacity to cause disease in susceptible hosts. It has the ability to adapt to and thrive in many ecological niches, from water and soil to plant and animal tissues. The bacterium is capable of utilizing a wide range of organic compounds as food sources, thus giving it an exceptional ability to colonize ecological niches where nutrients are limited. Pseudomonas aeruginosa can produce a number of toxic proteins, which not only cause extensive tissue damage, but also interfere with the human immune systems defense mechanisms. These proteins range from potent toxins that enter and kill host cells at or near the site of colonization to degradative enzymes that permanently disrupt the cell membranes and connective tissues in various organs. In people with cystic fibrosis the most serious complication is respiratory tract infection by the ubiquitous bacterium Pseudomonas aeruginosa. CF is one of the most common fatal genetic disorders in the United States, affecting about 30,000 individuals. A comparable number of people in Europe also have CF. It is most prevalent in the Caucasian population, occurring in one of every 3,300 live births. The gene involved in cystic fibrosis was identified in 1989. Located on human chromosome 7, it codes for a protein called the cystic fibrosis transmembrane conductance regulator (CFTR). This protein, normally produced in a number of tissues throughout the body, regulates the movement of salt and water in and out of these cells. The abnormality in the CFTR gene alters the CFTR protein in people with cystic fibrosis. As a result, one hallmark of CF is the presence of a thick mucus secretion which clogs the bronchial tubes in the lungs and plugs the exit passages from pancreas and intestine s, leading to loss of function of these organs. Progressive lung disease is the predominant cause of illness and death in people with CF. Mucus blocks the airway passages and results in a predisposition toward chronic bacterial infections. Although the genetic defect underlying CF has been characterized, exactly how and why individuals become infected with Pseudomonas is unknown. The lungs of most children with CF become colonized by Pseudomonas aeruginosa before their 10th birthday. Chronic infection with these bacteria reduces an individuals quality of life, causing acute symptoms of cough, sputum production, and inflammation, which causes repeated exacerbations or episodes of intense breathing problems. Eventually leading to scarring and destruction of lung tissue and, ultimately, death. While it is clear that antibiotic therapy directed against these organisms lengthens the life span of individuals with CF, increasing antibiotic resistance develops. Although antibiotics can decrease the frequency and duration of these attacks, the bacterium establishes a permanent residence and can never be completely eliminated from the lungs. Management of cystic fibrosis lung disease requires a multipronged approach. Outpatient management of pulmonary exacerbation usually includes a combination of 2 IV antipseudomonal antibiotics (an aminoglycoside plus a beta-lactam), appropriate antimicrobial treatment, effective airway clearance, optimization of nutritional status, and anti-inflammatory therapies. Additionally, prevention of respiratory viral disease and avoidance of exposure to irritants, such as smoke, is recommended. Usual duration of therapy is 14 to 21 days, and clinical response is assessed by physical exam, pulmonary function tests, nutritional status, and exercise tolerance. Microbial eradication is not a therapeudic end point. Choice of antibiotics should be based on culture and sensitivity of the sputum. Emergence of antibiotic-resistant species, such as Pseudomonas aeruginosa, has required close monitoring of antibiotic susceptibility patterns and strict infection-control policies. Administration of chronic intermittent inhaled antipseudomonal therapy (tobramycin solution for inhalation), over a 6 month period was shown to improve FEV by 11.9%, decrease the bacterial density, and reduce hospitalization in CF patients chronically infected with Pseudomonas aeruginosa. Following 92 weeks of therapy with inhaled tobramycin, the mean % change in FEV was 4.7% above baseline. There was no increase in the utilization of antipseudomonal therapy despite an increase in MIC at

Abolishing Death Penalty essays

Abolishing Death Penalty essays The death penalty in the United States should never be abolished. Each year there are about 250 people added to death row and, roughly, only 35 executed. The amount of terminations needs to increase dramatically. Many civilizations practiced barbaric punishments that place the prisoner in excruciating pain. However, capital punishment has become more humane by leaps and bounds in these past years and has been abrogated by several countries, though it has caused crime to rise in most cases. Regardless of anti-death advocates, I am firmly against its abating for a plethora of reasons. Nationwide, prisons cost an exorbitant amount of money to maintain and operate. Supplement that cost with new arrivals, medical costs, and repeat offenders. Youre looking at an estimated 1.5 billion dollars annually. The majority of these funds are withdrawn through taxes from everyday middle-class citizens like you and I. Only a miniscule fraction of these inmates are executed yearly. Due to the aforementioned fact, more prisons are being built around the country to accommodate the constant influx of convicts. Long and short term studies have proven that the vast majority of these criminals are released to only repeat their offense, soon after, and be returned to the facility that they just exited. A large percentage of prisoners cannot cope with the outside world after their release due to their incarceration period. On many occasions this has caused them to become extremely violent and, often times, commit a crime worse than the one they were imprisoned for. In every walk of life, in every part of the world, in every culture and civilization crimes against humanity are detested and combated in one way or another. Though, what most everyday people are unaware of is how luxurious our nations prison facilities are. If the steel bars, identical uniforms, and tranquilizer guns were taken away, they could be mistaken for ...

Prominent causes for the ending of the cold war Assignment

Prominent causes for the ending of the cold war - Assignment Example The research paper investigates leading significant causes that led the end of the Cold War.The primary international relations theories, liberalism and realism, possess contrasting views about the major causes for the ending of the Cold War, ranging from the US’ dominant military power to the Gorbachev’s liberal policies. In reality, the economic stagnation of the Soviet economic in the late 1970s and early 1980s mainly caused the early end of the Cold War In the early 1980s, during the period of Reagan administration, the bitter rivalry reached to such a height that majority of political experts and international relations theorists claimed the possibility of nuclear war between the two superpowers in the nearest future. On contrary, with the unification of Germany in 1989 and the collapse of the Soviet Union in 1991, the Cold War between the global powers ended even before the end of the 20th century. Such a decisive and unusually peaceful end of the Cold War was a surprising outcome from the perspective of modern political science and international relations theories, triggering numerous studies, researches, and theories that speculated various factors and causes that might have led the end of the Cold War Leaderships of Ronald Reagan and Mikhail Gorbachev, democratic and liberal ideologies, and economic factors have all been given as reasons for the ending of the Cold War. In reality, the economic stagnation of the Soviet economic in the late 1970s and early 1980s mainly caused the early end of the Cold War.

Couch Surfing the website Essay Example | Topics and Well Written Essays - 250 words

Couch Surfing the website - Essay Example The vision of the website is to see a world where everyone can explore and create friendships and connections with anyone that they encounter. The site has a rough estimate of about ten million users in more than two hundred different countries around the world. The site can be useful for students in student exchange programs and hitchhiking communities. Students and journalists use the site to meet new people, to hear about their travels, and make long lasting friendships. For professional journalists, this site can be of great use to them to learn about new places that they can visit. Website owners can use this website to create awareness for their websites. This is easy because one can generate traffic to their own website by connecting with friends on the social network site and directing them to website by providing web links. The platform is also useful for discussion forums where you can post pressing issues and invite friends to discuss them. This way, a student can get ideas about a project that needs assistance from the website

There was a perdominant clan mind set in appalchia and in turn Term Paper

There was a perdominant clan mind set in appalchia and in turn influenced feudings in appalchia. Scottish and irish and welsh im - Term Paper Example It is important to note that the Appalachians did not have trust in the justice system and hence resolved most of their issues of conflict with violence. Settlements 1The mountainous regions were invaded by the settlers from Irish, Scottish and those from welsh. The understanding of these earlier settlements in Appalachian is sometimes difficult with respect to the time they settled and the purpose for their immigration into this land. It is believed that the Irish and the Scottish were the first to settle within the mountainous regions. The main purpose for these settlements was to come and bring Christianity to their new found land and hence revolutionize the people who inhabited this region. It is also important to note that the settlers who came to this region were mainly Christians who loved music very much. Their purpose of civilization and the spread of their respective religious believes were however very futile. One important thing with these settlements however was noticed as music and the spread of music in this region; however, they found many challenges. There were very few churches as well as very few Christians and hence it was very difficult to establish themselves well. However, they mainly settled along the coastal regions along the North Carolina coasts, cape Fear River as well as Wilmington. However, few others found themselves in Appalachian highlands. These settlements were very important in the Appalachian since they affected the music of the Appalachian highlands as well as the life styles. The living styles were affected much by the Scottish and the Irish who came with the idea of Christianity and forgiveness. However, they faced challenges of remoteness and the inability to communicate efficiently within the region because of the physical barriers that were created by the mountainous topography of the place. However, Appalachian served as a new land for transformation since it resulted into the transformation of the people and their be liefs. It is however important to note that this took long time since the population was highly dispersed with reference to their population. 2Physical barriers served as the stumbling blocks to civilization and resulted into lack of trust for the legal systems that existed. Because of this, the option that remained for the people in case of conflicts and disputes was to resort to wars and violence. The mistrust they had with the legal system played a very important role in later years after settlement in the ignition of conflicts and violence that resulted into long periods of feuds as reported by researchers. It is also important to note that as new settlers, they did not only perceive courts and the systems as inappropriate but they also perceive d the people in the same way. 3Appalachia regions were isolated due to its topography and hence reaching there was not easy. This resulted into lagging behind other regions in terms of social, political and economic development. It is al so believed that these people were not well educated and hence there was no public awareness with respect legal system and the procedures to seek justice through the courts. Among all these, cultural beliefs and poverty played an important role in determining the way of life of the Appalachian

Experiment for Identification of Paracetamol

Experiment for Identification of Paracetamol PATRICK ANTWI MANU IDENTIFICATION OF PARACETAMOL THROUGH THE USE OF PHARMACOPIEA TEST ABSTRACT Paracetamol is widely used (NHS Choice, 2012) for the relief of minor pain, toothache, headaches, symptoms of cold and reduces of patient’s temperature (control fever symptoms). It is classified as a mild analgesic agent. The following procedures were used during the experiment of identification of paracetamol. TLC method is important for separation of mixture. This technique is commonly used to determine the presence of particular compound through comparison of Rf values of both unknown samples and the standard samples. Melting point analysis is also useful for identification of compound. The melting point range can be indicated and recorded with the help of a thermometer. For instance, the melting point of paracetamol ranges from168 to172 degree Celsius Infra-red spectroscopy is one of the most essentially useful methods for identification of compound. It is usually used to identify medicines that contain correct drug in most pharmaceutical industries. Structural information about the functional group of unknown compounds can be ascertained through the use of infra-red spectroscopy. Significantly, the results generated during this experiment attest the accuracy and importance of these methods for identification of compounds. For example, the Rf values of TLC method as well as infra-red spectroscopy analysis demonstrated the presence of paracetamol and cafeine in sample ‘B’ and ‘D’ respectively. INTRODUCTION Paracetamol is the best alternative choice for children and ulcer patients who have a minor pain such as headache and children. Consequently, too much it (NHS Choice 25/06/2012) can cause severe harm to the kidney and the liver. AIM OF THE EXPERIMENT Identify paracetamol from various unknown samples through pharmacopeia test. Hypothesis The range of melting point of the samples that contain paracetamol would be (168 to 172) degree Celsius. Again, the samples that contain paracetamol only would turn into violet without changing to red after the experiment D. The Rf values of unknown samples that contains paracetamol would be the same as the Rf value of the standard sample when compared. Apparatus used for the experiment Micro-spatula UV-light Indicator IR spectroscopy Melting apparatus Pencil Rule Chromatography tank TLC plate Thin capillary tube Conical flask Beaker Micro-pipette Materials used Ethyl acetate Four unknown samples Water Dichromate METHODS Melting point analysis Melting point analysis was conducted for all the four unknown samples labelled A, B, C, and D. Small amount of crystals of each unknown samples was fetched into the melting point capillary tube. The capillary tube contained the sample was placed into the melting point apparatus. The samples temperature was measured with digital thermometer. Hence, both initial and final melting point of the samples was observed and recorded. This experiment was repeated twice to obtain the ranges of the melting point. INFRA-RED TECHNIQUE During the experiment, the arm of IR spectroscopy was cleansed with (ethanol) alcohol. The background of IR spectroscopy was scanned. Hence, each sample was placed on the mouth of the IR spectroscopy and scanned. The wavelength detected the various bound in each compound. Copies of each compound scanned was printed out for observation and reading. EXPERIMENT D FOR IDENTIFICATION TEST ANALYSIS The experiment D was conducted for all the four unknown samples labelled A, B, C, and D. 0.1g of each unknown samples were measured with macro spatula and 1ml of concentrated hydrochloric acid was added to it. The solution was gently shake and heated to boil for about three minutes. 1ml of water was added to the boiling solution. After boiling, the solution was then placed in an ice bath to cool. Observation was made and there was no precipitation form. Therefore, 0.05m of 4.9/L solution of potassium dichromate was added to it and the colour developed for sample ‘B’ was violet without changing into red. However, the colour developed for sample ‘A’ was slightly red and changed to purpled whilst sample ‘C’ and ‘D’ developed yellow hint colour and diluted violet colour respectively. TLC METHOD A solvent system of about 20ml of ammonia: methanol: chloroform (1:19:80) was placed into the chromatography tank. A filter paper was placed against the wall inside the chromatography tank. The tank lid was placed on to prevent the evaporation of the solvent. The tank was left for about twenty minutes to allow saturated atmosphere to be formed. TLC method was conducted by using four unknown samples labelled A, B, C, D and ethyl acetate. During the experiment, a solution was made from each of the four unknown samples A, B, C, and D respectively. Thus, about 10mg of each sample was fetched with micro-spatula into the small beaker and dissolved with the small volume of ethyl acetate. Moreover, TLC plate was prepared by measuring 1.5cm distance from the edge of the plate with a rule. A horizontal line was drawn and marked the intervals with a pencil. The distance in between each interval was about 1.5cm apart. The line was demarcated into six intervals for the four unknown samples as well as the standard samples, which comprises of paracetamol and caffeine solution. Each solution was fetched with the help of a micro-pipette and spotted on the TLC plate at different intervals. In addition, the standard sample solutions of paracetamol and caffeine were spotted on the same plate at different position. Thus, spot A, B, C, D, Par and Caff in that order. The TLC plate was placed into the chromatography tank and covered with the lid. The solvent then moved up gradually through capillary action. Hence, the solute spotted on the TLC plate moved up along with the solvent (thus, mobile phase). TLC plate was removed from tank when the solvent reached about 2cm distance to the edge and marked with a pencil. Moreover, the plate was left to dry for about 20 minutes. After the evaporation of the solvent has taken place, TLC plate was then placed under the UV light for observation. A drawing was made with a pencil around the new spots formed on the plate. A measurement of the distance travelled by both solvent and substance were recorded. The Rf value was calculated for both unknown samples and the standard samples. Therefore, the Rf value was calculated base on the formula below. Rf value = distance travelled by substance divided by the distance travelled by solvent. Finally, the Rf values of unknown samples were compared with Rf values of the standard samples. The Rf value for paracetamol Rf = 3.90/6.1 Rf value = 0.639 = 0.64 RESULTS (b). Melting point analysis results SAMPLES A B C D MELTING POINT RANGE 171- 175 171 172 200 206 159 The sample ‘A’ is a bit higher than the normal range of the standard paracetamol sample. Equally, sample ‘B’ indicated the presence of paracetamol as the ranges 171-172 degree Celsius (c). (d). EXPERIMENT D FOR IDENTIFICATION ANALYSIS results SAMPLES A B C D Colour of solution Slightly red and turned to purple Violet Yellowish hint Dilute violet Sample ‘A’ developed purple colour which shows para-aminophenol The colour achieved for sample ‘B’ was violet which show positive result and it was therefore indicated the presence of paracetamol. The colour developed for sample ‘C’ was yellow hint which indicated the presence of caffeine. However, sample ‘D’ developed diluted violet colour which shows the presence of caffeine and paracetamol. Infra-red analysis results Sample AÂ   Sample B Bond Functional group Frequency / wave number absorption cm-1 Intensity v N-H amine 3319.12 stretch strong v C-H 2794.94 stretch strong/medium v O-H Hydrogen bond in alcohol, phenol 3109.51 stretch Strong v C=C 1650.71 Aromatic stretch s v C=O 1609.82 amide stretch N-H delta amide 1562.66 amide bend v C=C Aromatic stretch 1504.96 aromatic stretch The functional group obtained on sample ‘B’ indicated the presence of paracetamol. Sample C Sample D (g). Results for TLC analysis STANDARD SAMPLES Paracetamol Caffeine Rf values from TLC analysis 0.64 0.89 SAMPLES A B C D Rf values from TLC analysis 0.74 0.64 0.89 0.73 The Rf values calculated for TLC analysis indicated that sample B is paracetamol when compare with the standard samples. Thus, 0.64 Compound A, C, and D are less polar since they travelled faster and further in the mobile phase and they are more attracted to the mobile phase than compound B. However, compound B is more polar and travel slowly in the mobile phase. It is most attracted to the stationary phase. Discussion The experiment D of sample ‘B’ clearly showed positive outcome and indicated the presence of paracetamol as violet colour was achieved. In addition, TLC analysis also indicated that sample ‘B’ was paracetamol when Rf value of unknown samples ‘compared to the standard samples. Therefore, this shows the accuracy and precision of the positive outcomes of the experiment. Equally, the ranges obtained from melting analysis for sample ‘B’ also confirmed the presence of paracetamol. Experiment D of sample ‘A’ showed deep purple colour and the infra-red analysis confirmed that, it is para-aminophenol. Moreover, both experiment D, TLC method and infra-red analysis confirmed the presence of caffeine in sample ‘C’. However, sample ‘D’ developed dilute violet colour TLC analysis which shows a mixture of (two compounds) paracetamol and caffeine. The infra-red analysis also confirmed that, sample ‘D’ was a mixture of two compounds. Time SUMMARY REFERENCE Barber, J., Rostron, C.,(2013). Pharmaceutical Chemistry Hill, G., Holman, J,. (2011) Chemistry in Context. 6th edition NHS Choice, (25/06/2012). Available at: http://www.nhs.uk/Conditions/Painkillers-paracetamol/Pages/Introduction.aspx APPENDICES Mobile phase: Rf value: retention factor for thin layer chromatography. Stationary phase: TLC: thin layer chromatography UV light: ultraviolet light

Health Campaign Essay

Health Campaign three on diabetes serves to implement change in population health. The main focus of this presentation is on recommendations for implementing and assessing the change in population. The presentation is to discuss the various recommended implementations to improve the health of diabetic population by addressing the social, economic and cultural factors. The paper also recommends different approaches in place for the diabetic population such as the programs, policies, laws, and environmental aspects for assessing the health and wellness of the target population. The paper addresses several challenges related to improving the health of the diabetic patients by examining the global implications, environmental factors and disease prevention. Finally the paper summarizes the epidemiology and other data models used by the managers for decision making and to anticipate future trends. Mass media campaigns are the treatments based on mass media channels to present subjects abou t the physical activity to big and undefined audience. These campaigns are presented to enhance awareness and knowledge of the gains of the physical activity, and beliefs about the physical activity, alter physical activity behavior in diabetic populations. The subject matter can be channelized via as newspaper, brochures, manuals, radio, television, and websites or in a combination. Social support networks for diabetes using internet and mobile applications. Social support networks uses mobile applications for diabetes such as M-health for the daily monitoring and self-management of diabetes (Chomutare, et al., 2013). Economic factors include awareness of the direct medical cost and indirect medical cost for diabetic management is important for the population. Direct medical cost which is the average medical expenditures among people diagnosed with diabetes is twice as higher than the people without diabetes. Indirect cost is more than 69 billion which includes the cost for disability, work loss, and premature death (Center for Disease Control and Prevention, 2012). Building cross cultural relationships by one to one  interaction connects each other in a culturally diverse community. Building relationship with people from different cultures including the minority population is the key in building diverse community that are powerful enough to achieve the goals. Bringing quality of health care into culturally diverse community by sturdy and caring relationships based on the trust, understanding and shared goals (Noll, 2012). National Diabetes Education Program (NDEP) works with partners to reduce the burden of diabetes and to prevent or delay the onset of type-2 diabetes and its complications using proven approaches. National Diabetes Prevention Program partnerships with community organizations, insurers, health care organizations, employers and governmental agencies. The National Program to Eliminate Diabetes Related Disparities in vulnerable population assist community partners in planning, organizing, developing, implementing and evaluating community based interventions to decrease the incidence of diabetes. National Public Health Institution on Diabetes and Women’s Health enhances approaches to improve access and quality of care for women with gestational diabetes. Road to Health is designed for African American and Hispanics at risk for type-2 diabetes, which is a community outreach program reinforcing the prevention or delay of diabetes. Laws on nutritional labels provide information on carbohydrate counting and helps to compare foods and to make better choices. Food labels can be essential tool for diabetic meal planning (Center for Disease Control and Prevention, 2012). Environmental and policy approaches are planned to promote opportunities, provide support, and reminds people to be more physically active. Enhanced spaces for physical activity involves an attempt to change the existing environment to create physical activities, such changes include making walking trails, promoting exercise facilities, and providing access to existing nearby facilities. Environmental modification for creating walkable communities, increases physical activity levels by development of adequate trails, sidewalks, pedestrian spaces to bike, jog, and walk. The land use policies and practices involve the efforts of planning and health care professionals to change the physical environment of urban area to support physical activities. The land use policies should support improvement of ecofriendly spaces, increased sense of community, and increased consumer choices for places to reduce stress. Transportation and travel policies will facilitates walking, bicycling and use of public  transportation. Also, increased parking cost will promote the use of public transportation (Center for Disease Control and Prevention, 2012). The global rise in the non-communicable disease presents a tremendous challenge in public and private health care sectors. With complex and variable determinants of health non-communicable disease like diabetes is estimated to increase the global burden of disease and death rates. Diabetes accounts for more than fifteen percentage of National Health care Budgets, and almost triple the health care resources. Many of the countries have improved the health care infrastructure which is fragmented, but still it remains inadequately funded and non-operational. Environmental challenges include the lack of exercise, obesity, rapid Westernization of low and middle income countries and changes in diet habits (Tjota, et al., 2011). Encouraging public awareness about healthy diet, and promoting physical activity facilitates to overcome the challenges. Another challenge is the inadequate workforce in the public health sector, lack of adequate training on the disease prevention and health care promotion. Finally there is no enough evidence-based research materials to support the public health care for disease prevention and health care promotion. Translating Research Into Action for Diabetes (TRIAD) is a conceptual model that uses Donabedian’s paradigm to draw the relationships among various factors such as the system factors, process of care and health care outcome. The model is used for decision making in diabetes treatments, identify barriers and better care outcomes for the people with diabetes. This model is launched by Center for Disease Control and Prevention (CDC) and the National Institute of Diabetes and Kidney Diseases (NIDDK). TRIAD model is a cohort study in which the system factors include structure of the health care system, disease management steps, referral care and management, payment services and incentives, cost-containment steps and use of information system. In the process of care the model uses HbA1c testing, lipid testing, retinal examinations, micro albuminuria testing, annual foot examinations, and prescription of aspirin. The health outcome expectations include the glycemic control, blood pressure control, utilization and cost control, management of health status and symptoms, that includes cardiovascular disease, renal disease, retinopathy, and cholesterol control (Translating Disease Into Action for Diabetes Fact Sheet, 2011). Conclusion Diabetes has become an epidemic that continues to rise and become the seventh leading cause of death among the population. Federal, state, and local agencies have placed various surveillance systems and recommends to assess how diabetes affect the community and the specific targeted population. Diabetes as a public health issue is aligned with the nationally identified health objective of Healthy People 2010 and continues to address the issue with improved methods of prevention and control of the disease. The presentation recommended implementation of the campaign for diabetes based on the social, economic, and cultural factors. It also revealed the various approaches taken by policy makers, department of law, various diabetes programs, and environmental aspects involved. The presentation assessed various challenges in improving the population health. Finally the presentation summarized the TRIAD model used by the managers for decision making purposes and to anticipate the future nee ds. Reference Centers for Disease Control and Prevention. (2012). Diabetes Health Resource. Retrieved from http://cdc.gov/diabetes/status/us/index.htm. Chomutare, T., Tatara, N., Ã…rsand, E., & Hartvigsen, G. (2013). Designing a diabetes mobile application with social network support. Studies In Health Technology And Informatics, 18858-64. Noll, K. E. (2012). Cultural diabetes. (Order No. 1519974, University of Denver). ProQuest Dissertations and Theses, 86. Retrieved from http://search.proquest.com/docview/1112475764?accountid=458. Tjota, M. Y., Kozak, B. M., Chang, E. M., Wu, V. L., & Close, K. L. (2011). Journal of Diabetes NEWS. Journal Of Diabetes, 3(3), 174-181. doi:10.1111/j.1753-0407.2011.00140.x Translating Disease Into Action for Diabetes Fact Sheet. (2011). Diabetes Public Health Resource. Retrieved from http://www.cdc.gov/diabetes/projects/research.htm.

Playing an Instrument Essay

People have different reasons for doing things. Some believe that writing, playing instrument and eating give joy and happiness. When we talk of instrument, different things crop up, such as musical instruments, working instruments, manufacturing instruments etc. In this work, there will be comprehensive details about playing an instrument. We will focus only on playing a musical instrument. For this purpose, we will cover the different aspect of musical instrument. How people learn to play instruments, what benefits people get from playing an instrument, when to buy a musical instrument etc. There are different types of musical instruments, such as the guitar, keyboard, flute, saxophone etc. Musical instruments are of different types. We have the string instruments, wind instruments, percussion instruments etc. Under each of these groups, we then have different instruments. For instance, under string instruments we have the violin, harp and guitar. These instruments are played in different ways, for instance playing a piano involves buying a preferred type, installing, getting a good teacher to put one through and trying different styles and listening to music, which will give insight into how the instrument must sound when been played. In the world today, playing any type of musical instrument have become some lovers’ of music priority. People try to learn how to play a musical instrument at all cost. Then who can play an instrument? What is of paramount is the interest in learning to play. If the interest is not there then, playing or learning might be a problem. When this issue has been established, the next thing is getting a good tutor who can take one through the rudiments of playing such an instrument. There are things that should be put in place in other to learn how to play a musical instrument. One of such things is patience. This is one aspect should be taken seriously. In other, to learn anything in life the issue of patience cannot be taken for granted. You have to be patient. Another issue is the practice. You have to be repeating or practicing this act almost every time or everyday in other to master it. Learning to play an instrument is not a days or weeks job. This act has to be continuous and consistent for sometime until one is perfect. Another aspect is paying attention to the rudiments or skilled that will be needed in learning the instrument. There should be full concentration. However, people have different motives for learning how to play an instrument of any kind. In the context of our discussion, people desire to play instrument because of what they will get. These might come in form of financial reason, pleasure or happiness. Why some specific people may want to learn how to play instrument because of the financial benefit that is attached to it, others may what to learn how to play these instrument at leisure or for pleasure. Then what are the benefits of playing an instrument. One of such is that this act teaches discipline because playing an instrument is like trying to learn a new language, which in some cases can be demanding. Therefore, you have to be disciplined in other to learn how to play these instruments. Another benefit one can get from playing an instrument is can be having a sense of accomplishment. At start, when one starts to learn it might look like a challenge, but when the act is mastered, one can be proud of it. It can also be a means of exercise. Sometimes when we are strained out we can just try our hands on an instrument to cool off and relax. Moreover, there are different problems people may encountered when playing an instrument. For instance in buying a grand piano the issue of quality is vital. If you want buy any instrument there are some things that are vital and of most important. Quality is one of the things that are vital. In addition, costs and functions are also vital. For example, the work of a lead guitar is different from the bass guitar. There can also be problem caused by the instruments itself such as the bowing of the violin. These can be harmful on the part of the person playing it. In conclusion, playing of any instrument depends on different aspect of life: interest, skills and efforts. This write up has been able to give meaning to the phrase playing an instrument.

Moonlight Professor Ramos Blog

Moonlight Yes girl get me one more shot, says the girl at the bar. She has been drinking for over an hour straight and all she can think about is a man missing in her life but out in the open she looks very happy to be with her friends. It is Friday and she has been drinking all night nonstop, at this point she is stumbling and is about ready to call her friend to come pick her up.Sarah! Sarah! she screams. girl i need you to come pick me up, Im drunk and they are getting ready to close, says the girl. Okay Im coming right now just be outside in 10 minutes, answers Sarah. During the 10 minutes the girl at the bar was still slamming shots and ends up taking 3 more shots before she ends up leaving her wallet on the bar table. luckily she had her I.D in the wallet so the bartenders were able to determine who it was and were going to be able to keep it for her for next Friday. Sarah arrives and the girl stumbles into the car barely even able to walk on her own and Sarah proceeds to take her home after a wild night a the bar. A day later goes by and the girl realizes that she had left her wallet in the bar and plans to go next Friday to grab her belonging. a week goes by and she finally goes back to the bar to go get her wallet. she walks in and doesnt the wallet on the bar counter where she was drinking and now she starts to get a little worried that someone stole her wallet after 30 seconds of standing and brainstorming where her wallet could be she decides to go up to the bartender and ask to see if he had seen a wallet. He responds you are in luck young lady, about ten minutes ago a young man had turned it in to us and said he found it on the ground with footprints all over it. she replies o thank God! i thought i would have never gotten it back because usually bars are notorious for stealing wallets and valuable belongings. she asks the bartender if the man who turned in the wallet was still in the bar so she can go thank him for turning it in. the bartender pointed to a man that had been drinking w ith his friends and responds him right there with the navy blue shirt on and the tan khakis. She happily walks over to the man to thank him not knowing that he was actually the love of her life. She walks up to him and notices his gleaming white smile with nice slicked back hair. she was in complete awe as soon as she laid eyes on him. The man saw love at first sight also and he was surprised at the beauty in her wavy blonde hair and shiny nice nose piecing she had in at the time. In her head she was for sure she has seen her lover and on the other hand the guy was pretty sure he was going to have to get her number because he knew he wouldnt be able to lie with himself if he never got to see her again. In person they both kept composure and the conversation was going very smooth until the guy asks the girl for her number. at this point in the conversation the mans friends had moved to the other side of the bar to let them have there privacy. The man looked up after asking the girl t he question and sees her cheeks automatically start turning a pinkish red. the girl looks to him and instantly responds with her number. the guy says ill give you a call and returns to his friends on the other side of the bar and as he is walking back his friends are looking at him with a smirk on there face because they knew he got the job done 3 days pass and the girl is very nervous that the guy most likely wont hit her up again, she sets her phone on the table and goes in the kitchen to go do the dishes. when she hears her phone beep because she got a notification, and she checks her phone and its the gut from the bar and he wanted to know whether she would be happy to go get lunch with him. She responded absolutely i would love to go, Im free at 4 so you can come pick me up then. He answers sounds good. 4 oclock hits and he picks her up to go get some sandwiches. Everything was going very smooth and they connected vibes almost instantly on lunch and in the back of both there heads they knew they were perfect for each other. After the date was over the girl asked the guy if he would like to come over and his automatic answer was yes. at this point in the night it was 7:45 pm and they were driving back to the girls house to go have a little fun. As soon as they get to her house she grabs his hand and takes him upstairs in her room and they instantly start making out and touching each other until they end up in bed. They both are laying in the bed cuddling when suddenly they both calm down and both stair out the window and see the full moon out. He looks at her and says i love you Julia, and she whispers back to him ,I love you too Max.

External Environmental Analysis of Hallensteins

External Environmental Analysis of Hallensteins External Environmental Analysis of Hallensteins Hallensteins operates in an industry which is highly competitive. The performance of the market is highly affected both internal and external environmental factors. However, macro-factors have the potential of affecting the economic productivity of the firm (Dun Bradstreet, 2007). These external factors can be analyzed using the porters fives forces model. This model is essential in conducting an industrial analysis of the clothing market of New Zealand. Using this model, Hallensteins economic and industrial performance can be analyzed as discussed below. Competitive Rivalry Just like the rest of the firms, globalization has affected the clothing industry of New Zealand. Using the porters model, competitive rivalry in the clothing industry (especially mens wears) affects the profitability and economic potentials of growth and development of Hallensteins. Amid this intense competition, Hallensteins has remained profitable over time. As noted by the CEO, the changes in the fiscal and monetary policy adopted by the government of Australia and New Zealand had impacted on the purchasing power of the consumers (Bollard, 2002). Hallensteins faces still competition from fashion and clothing firms such as DHL Express Fashion Export Scholarship. The clothing industry of New Zealand is a perfectly competitive industry with free entry and exit. The fashion and mens wear traded in this industry have close substitutes which are highly differentiated. This allows for stiff and fair competition in the industry. The power of suppliers The suppliers determine the success of an industry. This is the same situation in the fashion industry where Hallensteins operates. Hallensteins depends on both imports and exports as their main suppliers. This implies that the industry operates in a fairly competitive industry with respect to supplies (Roy, 2009). Therefore, suppliers determine the success of Hallensteins through manufacturing quality products for both men and women and at the same time ensuing study supply of the much needed fashion and clothing essentials. The power of buyers A market only exist where there are willing and able buyers. Buyers are highly sensitive to price, quality and taste and preferences. For Hallensteins, the main group of customers is men. Given the competitive nature of this industry and the free accorded to the buyers, Hallensteins success rests on how well it match the changing needs of the customers in the fashion industry. Hallensteins target men as the most potential group of consumers because of their relatively higher purchasing parity and economic dominance (Rutland, 2005). Threats of substitutes Customers in the fashion and clothing industry of New Zealand have a variety of products and clothes to independently choose from. This gives them a chance of satisfying their diverse interests and preferences. For instance, there are range of mens shirts, coats, trousers, and shoes which consumers can choose form. Substitutes become a threat when their prices are relatively cheaper, and the consumers are ready to make a product switch. New Entrant Threat Since Hallensteins operates in a perfectly competitive industry with no legal barriers to entry or exit, other international fashion firms are free to enter the clothing industry of New Zealand. The entry of new firm or manufacturers is a big threat to the future success of Hallensteins as this would imply stiffer competition for the limited resources (Roy, 2009).

The Paintings of Rococo, Neoclassicism, and Romanticism Essay

The Paintings of Rococo, Neoclassicism, and Romanticism - Essay Example The essay "The Paintings of Rococo, Neoclassicism, and Romanticism" explores the Rococo, Neoclassicism, and Romanticism art. The subjects are well mannered, smartly attired, and joining in lighthearted conversation. "Pilgrimage by Cythera" draws the viewer into the scene with its non-threatening use of composition. Rococo paintings would often use a touch of nudity and coy scenes to elicit a feeling of naughtiness. The end of the 18th century witnessed a return to a more formal style of painting known as Neoclassicism. More serious subjects replaced the gaiety of Rococo and color became more dark and brooding. The "Oath of the Horatii", commissioned in 1784, was painted by Jacques-Louis David (Jacques-Louis David). It is a sharply contrasted painting with sharp edges and depicting conflict. The painting uses abrupt angles to capture a cold and rigid feeling. In David's painting we see the intricate attention to detail that is displayed in the architecture and the metal swords reflect the sharpness of the tone. The women are sullen as if saddened by an upcoming loss or introspecting on their subservient position that was common of the period. The period of 1800-1850 saw the introduction of Romanticism in art. The paintings were often directed toward nationalism and regularly used to portray historical events. In Eugà ¨ne Delacroix's "Massacre at Chios" we see Greeks waiting their impending slaughter by the Turks. The human form is more detailed and more serious. The colors are more realistic and haunting.

Evaluation of Routing Protocols Essay Example | Topics and Well Written Essays - 2000 words

Evaluation of Routing Protocols - Essay Example Evaluation of Routing Protocols There are many routing protocols available as they define ‘what a router will do and decided for a specific data packet’. There are two types of routing fundamentals on which these protocols are based, named as Static Routing and Dynamic Routing. The following sections contains advantages and disadvantages of each routing protocol specified along with its administrative distance, metrics, periodic updates, triggered updates, partial updates, VSLM / CIDR subnet masking and algorithms. As per network dictionary it is defined as â€Å"Routing Information Protocol (RIP) is a standard for exchange of routing information among gateways and hosts. This protocol is most useful as an â€Å"interior gateway protocol†. It is also knows as Interior Gateway Protocol (IGP). Frame Relay protocol is implemented for WAN networks associated with LAN internetworking. It functions on physical layer and data link layer of the OSI model, to endow with robust and efficient mechanism for transmitting data. The transmission encompasses multiple routers and switches. Moreover, this protocol is identical to X.25 protocol that activates stations located at the end to share dynamically the network and bandwidth available. Two techniques are associated with Frame relay: As it is based on packet switching, the two techniques are Variable length Packet technique and statistical multiplexing. However, frame relay